Prevalence of group A rotavirus, enteric adenovirus, norovirus and astrovirus infections among children aged five years and below in Mukuru slums Nairobi Kenya

Gikonyo N.J, Nyangao O.J, Mbae C, Ngeranwa J, Njagi N.M.E, Kariuki M.S


Gikonyo N.J[1], Nyangao O.J[2], Mbae C[3], Ngeranwa J[1], Njagi N.M.E[1], Kariuki M.S[3]

  1. Department of Biochemistry and Biotechnology, Kenyatta University
  2. Center for Viral Research,Kenya Medical Research Institute
  3. Center for Microbiology Research, Kenya Medical Research Institute

 Corresponding author: Department of Biochemistry and Biotechnology, School of pure and Applied Sciences, Kenyatta University. Kenya. E-mail address: jngikonyo@gmail.com Tel no: +254721876506


  Summary

Enteric viruses have been recognized as the root cause of diarrhoea and a major worldwide menace responsible for childhood morbidity and mortality.  The aim of this study was to investigate the prevalence of gastroenteritic viruses in children below five years of age in and around Mukuru slums in Nairobi County of Kenya, and examine the association of prevalence with age, sex and season in this population. Stool samples from children in Mukuru slums were collected and screened for rotavirus, enteric adenovirus, astrovirus and noroviruses Genotype I and II using reverse transcriptase polymerase chain reaction. Rotaviruse was detected in 24%, enteric adenovirus in 2.7%, noroviruses in 1.7%, and astrovirus in 1.5% of the samples analyzed. These findings indicated that rotaviruses are the leading cause of viral gastrointestinal infections followed by adenoviruses, and noroviruses, enteric adenoviruses and astroviruses are important causes of acute gastroenteritis in Mukuru slums Nairobi Kenya. Further studies on viral pathogens in diarrhoea diseases for both outbreaks and sporadic cases should be carried out in order to understand the burden of viral gastroenteritis.

 Key words: Acute gastroenteritis, diarrhea, Rotavirus, Enteric Adenovirus, Astrovirus and Norovirus.

 [Afr J Health Sci. 2016; 29(1):134-145]

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3 Responses to Prevalence of group A rotavirus, enteric adenovirus, norovirus and astrovirus infections among children aged five years and below in Mukuru slums Nairobi Kenya

  1. jngikonyo@gmail.com says:

    I need full access to this paper. How do i go about it?

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